Coronary risk stratification, discrimination, and reclassification improvement based on quantification of subclinical coronary atherosclerosis – the heinz nixdorf recall study

This study sought to determine the net reclassification improvement (NRI) and improved risk prediction based on coronary artery calcification (CAC) scoring in comparison with traditional risk factors. It found that Coronary Calcification assessment results in a high reclassification rate in the intermediate-risk cohort, demonstrating the benefit of imaging of subclinical coronary atherosclerosis. Our study supports its application, especially in carefully selected individuals with intermediate risk.
AUTHOR
Erbel, R., Möhlenkamp, S., Moebus, S., Schmermund, A., Lehmann, N., Stang, A., Dragano, N., Grönemeyer, D., Seibel, R., Kälsch, H., Bröcker-Preuss, M., Mann, K., Siegrist, J., Jöckel, K-H (2010)
REFERENCE
J Am Coll Cardiol. 56(17):1397-1406.